I hope that tuxemon will become an awesome game and every awesome game needs a nice gameplay, so here are some ideas how touch input could work on the world (if you replace swipes with scrolling maybe for a mouse , too).
I'm currently reading through dive into python and will try to help with an implementation after this.
What do you think of this kind of control and what would you do differently?
(I hope the big pictures make no problems  )

• swipe to the left to open the menu
• (not the border more in the center of the screen, some OS's or DE's reserve swipes from borders)

• tap on the stairs (1) to go there and then downstairs
• tap on the black/not reachable place (2) nothing happens
• tap on the plant (3) go there and interact with it (maybe a second click to interact?)
• tap on a reachable sprite (4) go there

• when interacting:
• click anywhere (1,2,3) to get to the next text (if there is one)
• click and hold could skip the text?
• swiping could show previous text?

• tap on the tile before the door to exit

• tap in an open door to enter a house

• tap on a tile of the same type (1) to prefer this type
• tap on another tile (2,3) to go there (some algorithm is needed, maybe differentiation of double tap and one tap)
• tap on the end of a map (4) to change it to the next one
• tap between tiles (5) one of the tiles has to be chosen (randomly or the one wich is pressen "more"

• tap on a tile without a visible way to it (1,2) do nothing